Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Miro GTPases mediate mitochondrial attachment to motor proteins. @framattedi @alessio_vagnoni &co use photocleavable #Miro to inactivate it in fly neurons, revealing immediate consequences of its loss for #mitochondria, neurons & behavior #PLOSBiology https://plos.io/3seG2bE

🙏 Please help us spreading the word ...

Interested in Aging Research?

Aiming to understand age-related diseases & pathologies?

📣 📣 📣 Up to 12 positions for PhD candidates available in 2024!

Join our CGA in Cologne

https://www.ageing-grad-school.de/phd/applications/

@MPIAGE @CECAD
@UniKoeln
@agingresearch

#Biology #Aging #Ageing #Metabolism #Kidney #Altersforschung #Alternsforschung #Biochemistry #Genetics

“Never has the power to control public discourse been so completely in the hands of a few profit-seeking corporations with no requirements to serve the public good.” writes @Julia. “To prevent those who would hijack algorithms for power, we need a pro-choice movement for algorithms. We, the users, should be able to decide what we read at the newsstand.”
A must-read (gift link): https://www.nytimes.com/2023/08/17/opinion/social-media-algorithm-choice.html?unlocked_article_code=mT6ntAeiTg4MF3WsZFYZS5Gnpaxv1np12nE0KSei5IFsZ7aQkrlt5T2Z5OKGqoZUhzMe6BKTpIuRK68nJTtGy0nvdlrw5xKZyaiM86GDnl-FebhmJbRWoFug2vBc2aypC3D6pPF6PzDes7N--Bhl_QTsZEeiFFrNsrD_7gLm5wwCUdZ-EEijhFwIeUcVuVEdvwfyhzvhsXeth9Q78ayqTL5GY2lkFdSlcPElS1E3v-MbnYEFOd3OxGTl4UTm-EqtIImZsr_VFtGASplfk6hiMWwEhe3GHHM7JSD1oQvZnrr4igss9odWmTGy_2aJWBdB_4y61Y7P-B7xVppRbHBszOagXV8qVA&smid=nytcore-ios-share&referringSource=articleShare
#algorithms #socialmedia #MustRead

Our lab 🐌 now has a website and a logo: https://snailab.ca

Check out our website to learn more about our approach and research goals.

To give you a glimpse of the topics that interests us, we have also dedicate a page to the SNAIL Journal Clubs. We'll post summaries of the papers we read on this page: https://www.snailab.ca/home/journal-club

Cell-cell signaling needs to be precisely controlled for proper development & homeostasis. @melisa_degroot &co @CornellMBG show that the secreted Ca-binding protein SMOC regulates #BMPsignaling in #Celegans by binding to both BMP & glypican #PLOSBiology https://plos.io/47BOphw

'Crick Africa Network Fellows will receive four years of funding hosted at one of five African partner institutions: WACCBIP, University of Ghana; Stellenbosch University, South Africa; University of Cape Town, South Africa; MRC Unit The Gambia at LSHTM; MRC/UVRI and LSHTM Uganda Research Unit.'

https://www.crick.ac.uk/news/2023-08-14_the-francis-crick-institute-and-lifearc-partner-with-five-african-research-institutions-to-support-scientists

'The sriracha shortage is hardly the worst crop crisis that’s being fueled by climate change. For years, Michigan cherries have been suffocating in too-high temperatures, while Florida citrus have been obliterated by hurricanes; India’s wheat crops have roasted, while rice around the world has been double-teamed by floods and heat waves. But to now see peppers in peril is its own special burn.'

https://www.theatlantic.com/science/archive/2023/08/sriracha-shortage-hot-peppers-climate/675021/

'The coyote never orders the same product from the Acme catalog twice. “The President did not ask the Academy for advice about global warming again,” writes Jim Hansen, “during the remainder of his eight years in power.”

https://lithub.com/how-the-bush-administration-hid-the-dangers-posed-by-climate-change/

Lithographic print on wood 12x20cm

#Print #Printmaking #Art #ArtGallery #lithography #Handmade #artmastodon

https://madalenaparreira.com

M. #tuberculosis (Mtb) resists killing by repressing the #autophagolysosome machinery. @imgsb show that NCoR1 regulates these processes in myeloid cells by fine-tuning ATP homeostasis via AMPK-mTOR-TFEB axis, so controlling Mtb #pathogenesis #PLOSBiology https://plos.io/3quNEGD

Watercolor of a malignant growth springing from the eye of a woman, 19th century. The eye protruded for two months. In the righthand corner, you can see a monochrome sketch of the eyeball and tumour after its removal. [Image: Wellcome Collection] #histmed #histodons #histodon #history #medhist #histsci #illustration

Analysis of superspreading was crucial for COVID (and for many other outbreaks). As part of Epiverse we've therefore been collating functionality to easily interpret and summarise key features.

Feedback/contributions/suggestions welcome! See here for more: https://epiverse-trace.github.io/superspreading/

#IDMastodon @cdcgov Effectiveness of Monovalent and Bivalent #mRNAvaccines in Preventing #COVID19 Associated ED & Urgent Care Encounters Among Children Aged 6 Months–5 Years .VISION Network 🇺🇸 Jul 22–Jun 23
https://www.cdc.gov/mmwr/volumes/72/wr/mm7233a2.htm

'HIV is the easy part now — it’s all the aging stuff that’s coming up, but we hit those markers earlier than people who are not living with HIV. We’re classified as the silver generation, because we’re really the first generation of long-term survivors. So a lot of this is new to everybody. It’s new to the patients, it’s new to the providers. So we have to take a step back every now and then just realize we’re all learning this together.'

https://www.nejm.org/doi/full/10.1056/NEJMp2307347?query=featured_home

If you're UK Apocalypse Horsemen watch, here's one:

"Private equity firms have bought up dozens of UK healthcare companies including ambulance fleets, eye-care clinics and diagnostics businesses over the past two years"

https://www.ft.com/content/94184d66-517b-4893-8e06-df16efd135b3

‘Kind of Blue’. Released August 17, 1959.

#jazz #otd #MilesDavis #MastodonMusic

'Of note, CD20+ T cells are enriched in individuals with MS and in mice with experimental central nervous system (CNS) inflammation, and they have a highly activated phenotype2,3. In a recent publication, we provide evidence that these CD20+ T cells develop by an undirected transfer of B cell membrane termed trogocytosis, which takes place when B cells activate T cells during antigen presentation'

https://www.nature.com/articles/s41577-023-00920-7?utm_source=dlvr.it&utm_medium=twitter