Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Ending the climate emergency is possible: “We know that the obstacles to keeping warming below catastrophic levels are not yet physical and they’re not technological – they’re political. But there’s some pretty big political obstacles right now.”

https://www.theguardian.com/environment/2023/sep/30/human-civilisation-climate-scientist-prof-michael-mann

#climateChange #climateCatastrophy #climateEmergency #climateBreakdown #tippingPoint

"Although RBP-J is recognized as a key inhibitor of TNF-mediated osteoclastogenesis, the precise mechanisms that restrain TNF-induced differentiation of macrophages into osteoclasts are not fully elucidated. In this study, we identified that the Notch ligand Jagged1 is a previously unrecognized RBP-J target."

https://journals.aai.org/jimmunol/article-abstract/doi/10.4049/jimmunol.2300317/265946/Jagged1-Acts-as-an-RBP-J-Target-and-Feedback?redirectedFrom=fulltext

"Indeed, I started to avoid writing as much as possible, and was genuinely worried that my problems with writing would stop me from becoming a good scientist. I know I missed out on several job opportunities and conferences, for example, simply because I couldn’t bring myself to put together a cover letter or an abstract."

https://elifesciences.org/articles/92931?utm_source=linkedin&utm_medium=social&utm_campaign=organic

Interesting study looking at disinformation and likelihood of taking up non conventional ‘treatments’ and avoid vax that extends previous studies suggesting it’s partisan. ‘Endorsement of vaccine-related misinformation, mistrust of health care institutions and scientists, and conspiratorial thinking related to politics were all associated with greater likelihood of using non–evidence-based treatments.’ https://jamanetwork.com/journals/jama-health-forum/fullarticle/2809985

'Unlike bread-and-butter issues like wages, benefits and the terms and conditions of employment — topics over which management, according to labor law, must negotiate “in good faith” — technology, like business strategy, constitutes managerial prerogative. This means that the use of technology, such as artificial intelligence, exists in a bargaining gray area. If workers bring it up, employers can either open a negotiation or reply with a simple “No, thanks.” But the W.G.A. deal put A.I. squarely on the table.'

https://www.nytimes.com/2023/09/29/opinion/wga-strike-deal-ai-jobs.html

The electron microscope is a prop, the Publico feature is on the future of PhD programs, a discussion the IGC hosted during the celebration of 30 years of the international program Antonio Coutinho created for the Gulbenkian in 1993.

https://www.publico.pt/2023/09/28/estudiop/noticia/programas-doutoramento-igc-celebrar-passado-olhos-postos-futuro-2064313

"In 2017, almost a hundred years after insulin was ‘defensively’ patented for the express purpose of preventing unethical profiteering, Alec Smith was found dead in his Minneapolis home at only 26 years old. He had been diagnosed with T1DM two years previously, but seemed to have adapted well to the demands of insulin treatment. What had gone wrong? Smith’s great misfortune was that he had been lucky enough to be born a citizen of Earth’s wealthiest nation."

https://lithub.com/one-of-the-single-most-expensive-substances-on-the-planet-the-insulin-crisis-of-the-21st-century/

Mask by @madparreira

#Theater #SetDesign #HandMade #ArtGallery #TheaterArts #artmastodon

https://madalenaparreira.com

@joan_friedman @Teri_Kanefield

France isn't the only country with anti-democracy billionaires allied with foreign despots and malign petrostates.
https://www.cnn.com/2023/09/29/business/bernard-arnault-investigation-russian-businessman/index.html

Trump donor Harold Hamm resents efforts to act on climate because it hinders his abilities to make the planet uninhabitable for human life.
https://www.forbes.com/sites/christopherhelman/2023/09/29/billionaire-harold-hamm-on-how-biden-is-holding-american-energy-hostage/?sh=55230dde29ce

'Records that might have thrown a crucial light on key decisions taken by the UK government were mysteriously destroyed during the 1980s and 1990s when legal developments in other countries seem to have raised fears in Whitehall that officials might be found liable.'

https://www.ft.com/content/cd374a7f-69c3-466b-9dec-e106213b444c

Job at EMBL-EBI

"As Human Genomics Team Leader, you will be responsible for a multidisciplinary team of approximately 20 individuals, which includes software developers, bioinformaticians and data curators."
#sciencejobs #bioinformatics

https://www.embl.org/jobs/position/EBI02174

TIL that "galapago" means tortoise. Thus, "galapagos tortoise" translates to "tortoise tortoise". The islands were named after the tortoises and afterwards, these tortoises were named after the islands.

https://en.wikipedia.org/wiki/Gal%C3%A1pagos_tortoise
#til #todayilearned
https://www.reddit.com/r/todayilearned/comments/16vdo57/til_that_galapago_means_tortoise_thus_galapagos/

Convergent Evolution in a Murine Intestinal Parasite Rapidly Created the TGM Family of Molecular Mimics to Suppress the Host Immune Response https://doi.org/10.1093/gbe/evad158 #science #evolution #biology #genome #evolgen_paper

Let's try this again...

Thread on article: “The strain on scientific publishing” - out now.

Tagging @TheConversationUK @OverlyHonestEditor @GaltierNicolas @DORAssessment @ElisabethBik @brembs @mattjhodgkinson @danielbolnick @deevybee

Boosts much appreciated!

First, things first: growth in articles published each year has outpaced the scientists doing the publishing. With #PublishOrPerish, we all face an ever-increasing workload (writing, reviewing, editing…). It’s been rough.

Strain itself is neutral: this could be a welcome change! Are we becoming more efficient? Are we combatting biases (academic racism, positive result bias)?

If that’s all it were, the solution to strain would be to build a better infrastructure.

But… well… it’s not. 2/n