Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Tools

"CompRELEASE enables complex control of protein secretion and enhances the potential of synthetic protein circuits for therapeutic applications, while minimizing the overall genetic payload."

#Preprint

https://www.biorxiv.org/content/10.1101/2023.10.04.560774v1

Boar candlestick holder by @hunchbacksociety

#Ceramics #stoneware #pottery #Handmade #Art #stoneware #artgallery #artmastodon

https://madalenaparreira.com/Hunchbacksociety

In interviews, Katalin Karikó remarkably expresses no bitterness about her experiences. Just a clear focus on the goal of using mRNA to treat human disease. https://www.pnas.org/doi/10.1073/pnas.2119757118 #Nobel #science

'The snub was about more than just gender, according to Ms. Moss. “It’s easy to say she (Lise Meitner) didn’t get it because she was a woman,” Ms. Moss said. “One doesn’t think a woman is going to make noise about things.” Ms. Moss also believes Meitner’s heritage was at play: “This is a case where it was because she was a Jew.”

https://www.nytimes.com/2023/10/02/science/lise-meitner-fission-nobel.html

"Perhaps crypto was a legit fountain of wealth and success – perhaps it was moneyball for money, in which a new gang of smart rationalists were outfoxing traditional investors. Which made Sam Bankman-Fried, the lord and saviour of these renegades, a perfect Michael Lewis character."

https://www.theguardian.com/books/2023/oct/03/michael-lewis-sam-bankman-fried-crypto-going-infinite

"His book is a masterful demonstration of the great potential of the new military history that has emerged over recent decades as scholars, distancing themselves from an older generation mainly interested in chaps and maps, have begun to pay more attention to the social, economic, and political aspects of war."

https://www.nybooks.com/articles/2023/10/19/is-prussian-militarism-a-myth-iron-and-blood/

Preliminary results from the Denver Basic Income Project that's providing cash to hundreds of unhoused people for one year, using the first 6 months of data:

• NO ONE receiving $1,000/mo still sleeping outside
• Full-time employment increased
• Fewer visits to the ER
• Fewer nights spent in jail
• Reduced use of social and public services

Read the full report: https://drive.google.com/file/d/1gqtOfZG2sSanWgUdzn-lx-pwSXZKabj-/view?pli=1

Great interview in Science with my friend, the artist Rob Kesseler. I still remember a great exchange with a student at Instituto Gulbenkian de Ciencia who watched how Rob created art starting from images collected in collaboration with labs and let out an exasperated "You cant do that!".
Rob calmly replied "I can, I'm an artist".

https://www.science.org/content/blog-post/no-one-ever-asked-monet-if-they-were-false-colors

"La vacuna comenzó a inocularse en abril en Ghana. Y hay 18 países africanos que ya están solicitando dosis a través de GAVI. La OMS espera que con la mayor producción que comenzará a mediados del año que viene, más Estados se sumen a esta lista."

https://elpais.com/planeta-futuro/2023-10-04/la-nueva-vacuna-contra-la-malaria-abre-la-puerta-a-llegar-a-todos-los-ninos-que-la-necesitan-en-africa.html

'If Sunak had pissed about any longer, the Netflix doc about the decision could actually have come out while he was still droning on about not having decided it. This would have ripped a tear in the events-to-content continuum, reversing the natural direction of travel, and effectively ceding control of the UK to Netflix CEO Ted Sarandos. Then again, maybe it would be an upgrade. At this rate, the best hope for the country might be for Ryan Reynolds and the other one to buy us and use us as a content farm.'

https://www.theguardian.com/commentisfree/2023/oct/03/rishi-sunak-nigel-farage-liz-truss-hs2-brexit-netflix-conservative-conference

Mask by @madparreira #arts #theater #theaterarts #artgallery #handmade #artmastodon

https://madalenaparreira.com/set-design

On this day in 1930: June Almeida born, electron microscopy pioneer, took first image of human coronavirus, rubella virus and uncovered hepatitis B virus s

Shocking story about mRNA pioneer/Nobel winner Katalin Karikó, whose early advisor at Temple tried to have her deported & derailed her career because she dared to look for a better-paying job.

Later, UPenn demoted her, then forced her out, because her research wasn't bringing in enough funding. #NobelPrize #science [HT Paul Novosad]

#^Pomological


This Aeon Video exclusive explores the history and legacy of a beautiful project to record thousands of new fruit varieties
- by Aeon Video

Watch at Aeon

#IDMastododon #Viralimmunology #Immunology #Drugdevelopment The activation of #Bcells upon the binding of antigens to the B cell receptor (BCR) is important for vaccine-based #antibody production. B cells are more strongly activated by membrane-bound than by soluble antigens 🧵