Thiago Carvalho @cyrilpedia@social.cleverlibre.org

'Disinformation campaigns — some armed with AI-generated deepfakes — are likely to be rampant in the coming months, says Ulrike Klinger, who studies political communication at the European University Viadrina in Frankfurt (Oder), Germany. “And we cannot monitor them because we don’t have access to data.”

https://www.nature.com/articles/d41586-023-03102-6

'In a bid to stem the resurgence of sexually transmitted infections, the Centers for Disease Control and Prevention plans to recommend doxycycline, a widely used antibiotic, for use after an unprotected sexual encounter.'

https://www.nytimes.com/2023/10/03/health/doxycycline-syphilis-gonorrhea-chlamydia.html

'RNA’s fleeting nature isn’t a big problem for a vaccine: it needs to encode proteins only for a short time to trigger an immune response. But for most therapeutic applications, it would be much better to have RNA that could stick around for longer.'

https://www.nature.com/articles/d41586-023-03058-7

Faculty Position, Department of Pediatric Medicine - Division of Anesthesiology

St. Jude Children's Research Hospital

See the full job description on jobRxiv: https://jobrxiv.org/job/faculty-position-department-of-pediatric-medicine-division-of-anesthesiology-5/?feed_id=60996

#ScienceJobs #hiring #research
Memphis #UnitedStatesUS #FacultyMember #GroupLeader #PrincipalI...
https://jobrxiv.org/job/faculty-position-department-of-pediatric-medicine-division-of-anesthesiology-5/?feed_id=60996

My brilliant colleague Benjamin Judkewitz tells us all about the smallest brain in the singing fish Danionella. #imaging #berlin #optogenetics

Registration for the Michael Ashburner memorial symposium is now open. https://www.eventbrite.co.uk/e/michael-ashburner-memorial-symposium-tickets-728856127297?aff=oddtdtcreator

Amazon and other online retailers will start charging customers in France a minimum delivery fee of €3 when ordering books online from Saturday when a new law comes into effect to support independent booksellers.

Before, Amazon charged a single euro cent for delivery.

The measure aims to give independent booksellers a fighting chance at competing with big tech companies like Amazon.

https://www.euronews.com/culture/2023/10/06/france-makes-amazon-charge-3-delivery-fees-to-protect-indie-bookstores

#France #Amazon #OnlineRetail #Books #BookStores #BigTech

Bernd has been pushing this point for a while, and I think he is right. Self correction is an important part of the scientific process and journals, funders, and institutions need to do more to encourage it.

'What can journals do to support both self-correction by authors and by the community? We have discussed this matter for a decade at EMBO Press, culminating in a workshop that recommended to make an explicit distinction between an author initiated- and an externally initiated- or even forced retraction. We use the term “withdrawal” for the former and reserve “retraction” for the latter.'
#scientificpublication #ResearchIntegrity
@emboreports

https://www.embopress.org/doi/full/10.15252/embr.202358155

[#VeilleESR #WRanking] L'Université d'Utrecht annonce son retrait du THE Ranking, souhaitant favoriser la collaboration plutôt que la compétition.

Elle est classée 66e mondiale dans ce classement.

https://www.timeshighereducation.com/world-university-rankings/utrecht-university

'Harmonized individual-level data from a global cohort showed that 57.2% and 52.6% of cases of incident cardiovascular disease among women and men, respectively, and 22.2% and 19.1% of deaths from any cause among women and men, respectively, may be attributable to five modifiable risk factors.'

https://www.nejm.org/doi/full/10.1056/NEJMoa2206916?query=featured_home

'The latest vaccine will now be rolled out on a wide scale to the countries in sub-Saharan Africa where children are at the greatest risk from malaria. Oxford university has a manufacturing agreement with the Serum Institute of India'
#Malaria #Vaccine #Immunology
https://www.ft.com/content/4a54139e-7da7-48d2-bba9-487bf88ed811

Evolution strikes again

"One of the most uncommon hinges of vertebrate Ig is that exclusively found in Antarctic fishes: IgM H chain has a remarkably long hinge region, ranging from 14 to 22 amino acid residues, highly polymorphic, and rich in prolines and glycines (Coscia et al, 2000; Coscia et al, 2011; Coscia et al, 2012). Given these peculiar features, the hinge region has been suggested to provide the cold Ig molecule with higher flexibility to exert its function at very low kinetic energy in the Antarctic environment."
#Preprint #Immunology

https://www.biorxiv.org/content/10.1101/2023.10.04.560855v1.full.pdf

Gene therapy targeting regulatory elements to promote fetal hemoglobin expression in sickle cell disease.
My latest Clinical Pipeline column at Nature Medicine

#DrugDevelopment #DrugDiscovery #Crispr #SickleCell

https://www.nature.com/articles/d41591-023-00088-6

On vaccines in today's Economist, worth a read https://www.economist.com/leaders/2023/10/05/in-an-ugly-world-vaccines-are-a-beautiful-gift-worth-honouring

The platform formerly known as Twitter has now removed headlines from article links. Because what people really want to do is waste time clicking a picture while completely uncertain about what’s behind it.

The most American story of all time. Grocery store and potato chip CEOs are worried about the impact of people taking recently FDA approved weight loss drugs on their profits.

A story where there’s no one to root for and whoever loses, greed wins.

Postdoctoral researcher position at Institut Pasteur in Paris

Institut Pasteur in Paris

Join us for a #postdoc at #institutpasteur. Learn about #immunogens and #herpesviruses, while having a ball and living in #Paris.

See the full job description on jobRxiv: https://jobrxiv.org/job/institut-pasteur-in-paris-27778-postdoctoral-researcher-position-at-institut-...
https://jobrxiv.org/job/institut-pasteur-in-paris-27778-postdoctoral-researcher-position-at-institut-pasteur-in-paris/?feed_id=60989

New article! Read Proof of concept for a single-dose Group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particles https://www.nature.com/articles/s41541-023-00744-5?utm_source=dlvr.it&utm_medium=mastodon in npj Vaccines