In her ECR Spotlight, Min Tan discusses her research journey from working with butterflies and fish to jumping spiders and lizards, how jumping spiders can move and remain camouflaged & her participation in citizen science in Singapore.
https://journals.biologists.com/jeb/article/227/1/jeb247153/340681
Relief etching on copper by @madparreira.bsky.social
#printmaking #etching #print #copper #art #artgallery #handmade
Implementation of pupylation-based proximity labelling in plant biology reveals regulatory factors in cellulose biosynthesis https://www.biorxiv.org/content/10.1101/2024.01.09.574788v1?med=mas
It's a great book:
"Zemon Davis’s book is about an impostor in the same century: eight years after a man named Martin Guerre abandoned his life in a small French village, another man turned up, claiming to be him."
https://www.nybooks.com/online/2024/01/07/new-money-medieval-merchants/
Tools.
'In zebrafish, the zGRAD degron system (18), adapted from the Drosophila deGradFP system (19), is used to target POIs tagged with a GFP-based fluorescent protein for degradation, using an anti-GFP nanobody fused to an F-box protein. The degradation of the POI is mediated through polyubiquitination and the proteasome. However, these approaches have not been tested on many endogenous targets in vertebrates (20, 21) and notably not on proteins integrated into tight subcellular structures such as the sarcomere.'
'La Comisión Europea acaba de aprobar 38 millones de euros que, durante los próximos tres años (hasta 2026), sostendrán la infraestructura digital puntera para estudiar el cerebro EBRAINS (European Brain Research Infrastructures), una plataforma de investigación colaborativa diseñada para hacer avanzar la neurociencia y mejorar la salud cerebral.'
'The story of how hydroxychloroquine was anointed the Trump administration’s miracle drug for the coronavirus pandemic is a distinctly modern tale of misinformation within a global information ecosystem beset by widespread uncertainty, fear, media fragmentation and hyper-partisanship. Belief in the drug’s potential to cure patients infected with the virus followed an extraordinary trajectory from a small study conducted in France (Trump’s “very good test”) to Silicon Valley social media influencers, Fox News and the largest bully pulpit: the White House'
https://www.theguardian.com/world/2020/apr/06/hydroxychloroquine-trump-coronavirus-drug
☀️ Good morning!
What causes morning sickness in pregnancy?
GDF15 linked to maternal risk of nausea and vomiting during pregnancy
https://www.nature.com/articles/s41586-023-06921-9
Supports putative causal role for fetally-derived GDF15 in nausea and vomiting of human pregnancy
'Nos termos do “acordo de atribuição de patentes e licenciamento”, a BioNTech – que desenvolveu uma das vacinas contra a covid-19 com base na tecnologia de ARN-mensageiro (mRNA) – adquiriu igualmente a “tecnologia adicional ADC (antibody-drug conjugate)”.
Yesterday, a major new study was released showing massive numbers of micro/nano plastic particles in bottled water. Here's that study:
https://www.pnas.org/doi/10.1073/pnas.2300582121
Today, bottled water lobbyists released a predictable, biased, response:
1. Stop picking on bottled water, plastic particles could be everywhere;
2. Maybe they're not bad sooo for human health, we don't know.
3. The methods used are new, so who really knows if the results are valid.
4. Keep drinking bottled water.
"Scientists found the thickly contextualised, sharply focused histories of now-discarded science irrelevant and indigestible. Historians bridled at the scientists’ demands for a mythologised and anachronistic version of the past. We think it’s time to restart the conversation, for the benefit of both scientists and historians."
https://aeon.co/essays/science-and-history-cannot-afford-to-be-indifferent-to-each-other
COVID was a ‘gendered pandemic’, with women carrying very different burdens to men. A three-year New Zealand research project aimed to overcome the urge to forget, and provide lessons for the future.
https://theconversation.com/wanting-to-move-on-is-natural-but-womens-pandemic-experiences-cant-be-lost-to-lockdown-amnesia-218510?utm_medium=Social&utm_source=Facebook#Echobox=1704838630
"Substack’s argument in response to the Atlantic article was a masterclass in how not to do it: the best way to defeat these ideas, it claimed, was through scrutiny. Frankly, if scrutiny was going to defeat neo-Nazis or the idea that the Cultural Revolution had some upsides, it would have done so already."
https://www.ft.com/content/648ec2c0-d71b-4dc6-af15-56fedc54eb2d
SEC Twitter account compromised, used to falsely announce approval of bitcoin spot ETFs
January 9, 2024
https://web3isgoinggreat.com/?id=sec-twitter-account-compromised
"The F.D.A.’s handling of Singulair illustrates systemic gaps in the agency’s approach to addressing troubling side effects from medicines approved long ago — and to warning the public and doctors when serious issues arise. The agency had flagged the 2020 warning label, known as a “boxed warning,” to physicians’ groups, but it had not required that doctors be educated about the drug’s side effects."
https://www.nytimes.com/2024/01/09/health/fda-singulair-asthma-drug-warning.html
Human fetal brain self-organizes into long-term expanding organoids
THE REAL LESSONS WE SHOULD DRAW FROM CLAUDINE GAY’S RESIGNATION. https://lpeproject.org/blog/the-real-lessons-we-should-draw-from-claudine-gays-resignation/
"Public health agencies have spent four years explaining to everyone that 'only the vulnerable' need to worry about things like Covid. Then they turn right around and refuse to protect the vulnerable."
And now everyone who got Covid is vulnerable.
https://www.okdoomer.io/the-great-abdication/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com