'Putin’s goal is not just a little more turf. Russia has a lot of that. His telos—his endgame—is the destabilization, the overcoming, of the whole Western order. This sounds fantastical to Americans because we’re an ahistorical people. That doesn’t mean we’re ignorant of history, although there’s a great deal of that, too. It means the categories with which we apprehend the world are not defined by the past, and we can’t really understand how it could be otherwise.'
https://www.vanityfair.com/news/2017/01/the-secret-source-of-putins-evil?ref=thebrowser.com
Guinessomics
""The present yeast used to make Guinness stout brewed in Dublin, Ireland, can be traced back to 1903, but its origins are unknown. To that end, we used Illumina and Nanopore sequencing to generate whole-genome sequencing data for a total of 22 S. cerevisiae yeast strains: 16 from the Guinness collection and 6 other historical Irish brewing."
'Here, we found that Mtb did not stimulate isolated human pDCs to produce IFN-I, but human neutrophils infected with Mtb-activated co-cultured pDCs to do so. Mtb-infected neutrophils produced neutrophil extracellular traps, whose exposed DNA is a well-known mechanism to activate pDCs to secrete IFN-I. We conclude that pDCs contribute to the IFN-I response during Mtb infection by interacting with infected neutrophils which may then promote Mtb pathogenesis.'
#Immunology
https://onlinelibrary.wiley.com/doi/full/10.1002/eji.202350666
'Health officials in Brazil have warned that the number of dengue cases in the country could hit a record 5mn this year as climate change and the El Niño weather pattern in the Pacific Ocean fuel the spread of mosquito-borne diseases.'
#Dengue
https://www.ft.com/content/2f3b9b80-7b9a-42d4-bf7f-ea8492a8da24
"It is a wonder that the ORI accomplishes much at all. Its current budget is $12 million per year to oversee work funded by NIH, a $48 billion agency. Add to that the frequent internal strife over ORI’s proper role and a directorship that has often been vacant, and one can see how its ability to be effective does not meet the expectations for upholding the integrity of research activities."
"Do ponto de vista do partido, não deixa de ser curioso que – depois de acusarem a classe política de apenas querer tachos e de não ser íntegra – sirva agora de porto de abrigo a esses mesmos, ou seja, aos políticos que apenas querem tachos e que não são íntegros."
https://www.publico.pt/2024/01/12/opiniao/opiniao/deputados-vergonha-2076556
"The group, bankrolled with $500 million from some of the wealthiest families in American business, has created a stir in the world of academia by dangling seven-figure paydays to lure highly credentialed university professors to a for-profit bounty hunt."
https://www.nytimes.com/2024/01/12/business/arena-bioworks-scientists-harvard-mit.html
'Yet many are less equipped to do so than in previous big elections, experts warn. Some, including Meta, trimmed their investment in teams dedicated to maintaining safe elections after the tech stock downturn in early 2023. In the case of Elon Musk’s X, content moderation resources have been cut back drastically as he vows to restore what he dubs free speech absolutism.'
https://www.ft.com/content/16f23c01-fa51-408e-acf5-0d30a5a1ebf2
Etching on copper by @madparreira.bsky.social
#printmaking #etching #print #copper #art #artgallery #handmade
madalenaparreira.com
Postdoctoral Researcher at the Casey Eye Institute
Casey Eye Institute
Come join us as a postdoc at the Casey Eye Institute!
See the full job description on jobRxiv: https://jobrxiv.org/job/casey-eye-institute-27778-postdoctoral-researcher-at-the-casey-eye-institute/?feed_id=69815
#gene_editing #molecular_biology #organoids #retina #stem_cells #ScienceJobs #hiring #research
https://jobrxiv.org/job/casey-eye-institute-27778-postdoctoral-researcher-at-the-casey-eye-institute/?feed_id=69815
Pro-Israel Effort to Smear Penn President Started Well Before Oct. 7
https://theintercept.com/2024/01/13/penn-palestine-writes-liz-magill/
Oldie but goldie.
Unveiling the role of #KRAS in #tumorimmunemicroenvironment.
https://www.sciencedirect.com/science/article/pii/S0753332223018565
"In their recent study, Kevin Aslett, a political scientist at the University of Central Florida in Orlando, and his colleagues found that people who used Google Search to evaluate the accuracy of news stories — stories that the authors but not the participants knew to be inaccurate — ended up trusting those stories more. This is because their attempts to search for such news made them more likely to be shown sources that corroborated an inaccurate story."
Genopyc: a python library for investigating the genomic basis of complex diseases https://www.biorxiv.org/content/10.1101/2024.01.11.575316v1?med=mas
Here's @davidallengreen on the legal context of the #HorizonIT scandal, focussing on a number of key issues from the presumption of computer evidence's veracity, to the problem with private prosecutions....
This is an excellent (and as always well-informed) digest of how the #PostOffice used (and was mostly advantaged) by a legal system that it used to hound & prosecute those it actually knew were not at fault.
"Not only is science today more expensive, but it is also bigger and more multidisciplinary. There is a need for researchers and entrepreneurs to collaborate. A growing number of incubator and accelerator programs offer networking, support and advice to early-stage and mid-stage companies, globally, without the need for a lot of preliminary data."
Mapping the developmental trajectories of SAP-dependent innate-like gamma delta (γδ) T cells https://www.biorxiv.org/content/10.1101/2024.01.10.575073v1?med=mas
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com