Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
“I personally don’t believe that in a time of pandemic there should be exclusive licenses,” the researcher Adrian Hill declared to the New York Times in the spring of 2021. Hill and others at Oxford University, UK, had produced what was then the world’s leading covid-19 vaccine candidate and planned to offer it to manufacturers royalty free. But the insurgency was put down before it ever got off the ground.'
Thiago Carvalho
boosted
Hullo. So this is Mastodon, eh? Well, I'm here. And to celebrate, here's a photo I took yesterday in Kingston NY of Good Omens director Douglas directing An Unnamed Actor (on the other side of the glass) in Episode 2 of Good Omens Season 2 (Coming Next Summer).
Australia approves faecal grafts.
"The Therapeutic Goods Administration granted approval for faecal microbiota transplants as a low-risk biological for the “restoration of gut microbiota in the management of gastrointestinal disorders”."
Thiago Carvalho
boosted
RT @neil_gow
A pleasure to co- author this commentary with @ACasadevall1 arguing that the surface of fungi & bacteria is too complex and highly regulated to be adequately captured by the term “cell wall”. Your article link:
https://doi.org/10.1016/j.tcsw.2022.100087 @eurconfmedmycol @ISHAM_Mycology @MRCcmm
Thiago Carvalho
boosted
See link for nice curated lists of academics on Mastodon, with subjects ranging from Astrophysics to History to Law to Medieval History to Neuroscience.
Thank you to @hendrikerz and @perspektivbrocken for maintaining it.
"Here we show that individual Bmp ligands and Tgfβ drive distinct enterocytic programs specific to villus zonation. Bmp4 is expressed mainly from the center to the upper part of the villus, and it activates preferentially genes connected to lipid uptake and metabolism. In contrast, Bmp2 is produced by villus-tip mesenchymal cells, and it influences the adhesive properties of villus-tip epithelial cells and the expression of immunomodulators."
Thiago Carvalho
boosted
UCSF Faculty sent the following letter of strong support for students, specialists and postdocs to UC President Drake.
The most-compelling reason to increase the wages of postdocs and graduate students is equity. Having a less-than liveable wage makes advanced education inaccessible to historically underrepresented groups.
#UCOP #UCStrike#UCSFFaculty #UCStudents #UCPostdocs
Thiago Carvalho
boosted
From the outset, the bioRxiv vision has been to decouple dissemination and peer review. It's a sign of how far things have come that there'll be an entire HHMI meeting on preprint review (Dec 1-2) - which you can stream https://www.janelia.org/you-janelia/conferences/recognizing-preprint-peer-review
Thiago Carvalho
boosted
A cell photographed through a microscope. Actin filaments (blue), DNA in the nucleus (red), and the Golgi apparatus (yellow) are shown. #CellBiology
Thiago Carvalho
boosted
#introduction I’m a researcher in molecular #evolution investigating poorly annotated parts of bacterial and viral genomes, including short & overlapping genes, to better understand gene origins & regulation. Interested in more opportunities to review papers or present my research! SEED postdoctoral fellow, Wellcome Sanger Institute, Cambridge. https://scholar.google.com/citations?user=iwAIB78AAAAJ&hl=de #MolecularEvolution #postdoc #reviewing #genomics #bacteria #research #science
"The exhibition is, in essence, an installation of museum-approved counterfeits, products of research for springboarding imagination about what the ancient world may have looked like. But most of the reconstructions feel brand-new—unweathered and therefore unreal. They serve as components of an art-historical argument, rather than as art per se."
https://newcriterion.com/blogs/dispatch/chroma?ref=The+Browser-newsletter
Thiago Carvalho
boosted
Calling #genetics people. Faculty post a York University in Toronto. Great department. Send me a message if you want information. https://www.academicwork.ca/jobs/assistant-professor-genetics-york-university. molecular, cellular, and/or #EvolutionaryGenetics #genetics or #Genomics feel free to retoot to spread it further.
"To identify genes limiting T cell function, we conducted genome-wide CRISPR knockout screens in human chimeric antigen receptor (CAR) T cells. Top hits were MED12 and CCNC, components of the Mediator kinase module. Targeted MED12 deletion enhanced antitumor activity and sustained the effector phenotype in CAR- and T cell receptor–engineered T cells, and inhibition of CDK8/19 kinase activity increased expansion of nonengineered T cells."
#Immunology #Tcell #CARTcells
Thiago Carvalho
boosted
Didn't really spam # properly at 1st, & now realize how useful that is in 🐘 :
I study #immunity #genes and #immune #evolution, including host - #pathogen interactions. My work has focused on #antimicrobial #defense #peptides which are #antibiotics coded by the #genome . A key focus in #microbiome 🦠 , and #inflammation & #NFkB in #aging and #senescence .
Focus on #Drosophila but work in other #species whenever possible to improve evolutionary context.
Thiago Carvalho
boosted
#Introduction toot.
I'm a molecular virologist studying #BSL4 pathogens, primarily #filoviruses like #Ebola #Lloviu and #Marburg viruses at the #NEIDL at #BostonUniversity
I'm a big proponent of collaborating and #OpenScience
I love exploring the outdoors; #camping #hiking #kayaking #snowshoeing
I also enjoy #gardening and #brewing beer and cider.
I'm a huge #nerd at home too: my non-science reading list is mostly #nature #sciencefiction and #fantasy and I play #dungeonsanddragons
Thiago Carvalho
boosted
Folks interested in #CancerDrugDevelopment should check this months edition of #MolecularOncology 👇
https://febs.onlinelibrary.wiley.com/toc/18780261/2022/16/21
A thematic issue with excellent reviews on #DrugResistance #DrugDevelopment and #DrugDesign
We also contributed a review on targeting dNTP #metabolism in cancer, which we discuss in the context of (selectively) inducing DNA lesions in cancer cells and in the refinement of current antimetabolite based therapies
Thiago Carvalho
boosted
@ondinecleaver2022 @DenisDuboule @opourquie @RogersLabUCD @HaoYin @scottbarolo @kkroll @SpagnoliLab @Mill_lab @jamesbriscoe @MokalledLab @AaronJohnson @ebardot Ondine, we could pull the followers and followed by the Twitter SDB account and have it as a CSV file people can use to merge their follows. What do you think?
Thiago Carvalho
boosted
#introduction time!
I am a #social systems biologist.
I study how #evolution created #sociallife.
I study #ants and ant colonies as a model for #development.
I study the evolution and impact of socially transferred materials (e.g. milk, eggs, seminal fluid).
I lead the Lab of Social Fluids at University of Fribourg.
I am also the founder of The Catalyst, a science entertainment collective.
I am passionate about #scicomm, #genderequality, and making #academia a better place.
Thiago Carvalho
boosted
#introduction Hi fellow mastodonians!
I'm a neuroimmunologist with a focus on #Tcells in #multiplesclerosis. My lab uses #Tcr-seq , #antigen discovery, and in vitro and in vivo models to study the functions of T cells in MS with the goal of developing novel #biomarkers and targeted #therapeutics.
Here for communicating basic and translational science with like-minded folks. Looking forward to connecting!
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
