Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Postdoctoral position - Drosophila - neurodegeneration

Come join us in #NYC as a #drosophila postdoc, with a focus on #neurodegeneration.

https://jobrxiv.org/job/new-york-university-grossman-school-of-medicine-27778-postdoctoral-position-drosophila-neurodegeneration/?feed_id=29876
#ScienceJobs #ScienceJobs
New York, #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/new-york-university-grossman-school-of-medicine-27778-postdoctoral-position-drosophila-neurodegeneration/?feed_id=29876

If anyone fancies watching a beautiful 6 minute scientific video about #SARSCoV2 life cycle, this is really quite absorbing... #COVID19 #IDMastodon #virology
https://youtu.be/k2GlafQ9YhY

What determines our organs' architecture? How can we measure, predict, and manipulate it? Scientists around Keisuke Ishihara @IshiharaKsk from the lab of Elly Tanaka (@tanaxolotl) have tackled the question using neuroepithelial #organoids. (1/4)
https://www.nature.com/articles/s41567-022-01822-6

Enterovirus D68 (EV-D68) is clearly associated with the childhood paralysis disease Acute Flaccid Myelitis. However, the upsurge in EV-D68 infections this year has not resulted in more paralytic disease, and we do not know why. Hear a clinical perspective here: https://www.youtube.com/playlist?list=PLV5owftAGKzaJXz3_x4sOv0UrcdPweuD_

#AFM acuteflaccidmyelitis.org

and an #introduction to my lab! https://www.crowley-lab.org/
My lab is made up of an amazing diverse group of trainees. They are working on projects related to basal peptide signaling (Dakota), circuit pertubations caused by adolescent binge drinking (Dr. Seemiller, Avery), & neuropeptide changes with aging and #neurodegeneration (Grace) plus two amazing technicians (Keith, Dani) and many stellar undergraduates. We're also very interested in new #tech development for #neuroscience #technology #STEM

Deadline to apply for the HHMI Hanna H. Gray Fellows Program is 12/7/2022 https://www.hhmi.org/programs/hanna-h-gray-fellows-program
Please apply - this is a great program!

I don’t understand why people think Mastodon is difficult. It seems pretty straightforward, and the separate servers are no biggie. I’m enjoying this fresh start here, like moving to a new apartment!

My episode on the podcast "Big Picture Science" is about how a trickle-down approach to vaccination failed.

It reminded several people I spoke with from South Africa, Malawi & India of the worst days of HIV, when drugs were only available for rich countries. https://podcasts.apple.com/us/podcast/vaccine-inequity/id73329638?i=1000586910937

A new report from Stanford argues for changing how we teach science in the face of rampant disinformation. “…the goal of science education must be to make “competent outsiders” of all students.”

Focus should be on how to determine whether a source is credible.
https://www.science.org/doi/10.1126/science.abq8093

Full report: https://sciedandmisinfo.sites.stanford.edu/sites/g/files/sbiybj25316/files/media/file/science_education_in_an_age_of_misinformation.pdf

#NewPaper -- we use #ExperimentalEvolution to show:
-- gaining a tetracycline efflux pump by HGT is super costly for Staph aureus in low oxygen environments
-- treatment with tetracyclines prevents evolutionary adaptation to low oxygen (via gyrB mutation)

Possibly explains why tetracyclines remain useful treatments for Staph aureus infections that are often characterised by #hypoxia

Led by amazing PhD student Rebecca Hull

#Staphylococcusaureus #AMR #antibiotics

https://journals.asm.org/eprint/N8RXMPWTFJWVHZUAN55G/full

#introduction
I am neuroscientist and engineer. Our lab at Johns Hopkins University BME is interested in how the brain computes information about the world and how this representation is shaped by sensory experience from early development up until old age. We focus on the auditory system and use in vitro and in vivo optical and electrophysiological methods, behavioral approaches, etc.

www.kanold.org

#neuroscience
#auditory
#auditoryneuroscience
#crossmodal
#hearing
#cortex
#JHU
#JHUBME

Some Mastodon tips I've learned:

- You need a fit, young hunting party
- They are not easy to bring down, so make sure your spears have extremely sharp tips
- Ensure you have a supply line and pack animals available to transport the meat and pelt back to the cave

Just arrived here on Mastodon so here's an #introduction! Total Internal Reflection (TIR) is a #science #blog (http://totalinternalreflectionblog.com) but one that focuses on the human side of science instead of research.

Posts typically fall into two types - either commentary/opinion (sometimes silly, sometimes serious), or #HowTo guides aimed at improving young scientists' #SoftSkills.

I'll be highlighting new postings here, and would be delighted to get comments/feedback/input - the blog is all about starting a discussion rather than having the last word.

#introduction

I think about how a collective of agents (animals, neurons, mathematical structures) can solve problems. Additionally, I am interested in what it means to produce a good model and understanding of something.

I am excited to be here to learn and discuss.
#Neuroscience, #CollectiveBehavior #CollectiveIntelligence
#ComputerScience
#maths #mathematics #logic #algebra #CategoryTheory #types
#machinelearning #computervision
#symbolicAI
#CognitiveSystems
#AI #ArtificialIntelligence

Please boost:

Who else on here works on #phylogenetics?

Maybe do a quick post with what you work on (e.g. clades, methods, questions...), and include the hashtag #phylogenetics so we can find and follow each other. Feel free to link to a paper or two!

For my part - I work on model selection, phylogenetic algorithms, mixture models, and at the moment am mostly working on the problem of how you find >1 tree in a single alignment, e.g. our latest attempt https://www.biorxiv.org/content/10.1101/2022.10.06.511210v1

I just read @DavidLowry 's excellent 2012 review of the evolution of the #ecotype concept, from Turesson and Clausen, Keck and Hiesey through Stebbins, Grant, Raven, Levin, Wu, Mallet, Schemske, and the early genomic era.

A good reference if you are interested in how #biosystematics connects to modern studies of plant #speciation and #species concepts.

#botany #plants #taxonomy #systematics

https://doi.org/10.1111/j.1095-8312.2012.01867.x