Thiago Carvalho @cyrilpedia@social.cleverlibre.org

'Scotland’s boost in vaccination rates during lockdown is probably linked to flexible working for parents (which enable them to attend vaccination appointments) and mobile vaccination centres. A real push to make vaccination clinics easily accessible to parents is also how Pakistan and Uganda have maintained their levels over the past few years.'

https://www.theguardian.com/commentisfree/2023/mar/27/vaccines-work-children-covid-decline-england

"O Banco Central Europeu defende interesses e podemos ter a certeza que não são os das pessoas ou, como agora se diz tanto, os das famílias. Para quem tem dúvidas: reparem que ainda na semana passada, e enquanto anunciava o aumento das taxas de juro, Lagarde apelava ao fim dos apoios governamentais às famílias e às empresas."

https://www.publico.pt/2023/03/27/opiniao/opiniao/senhora-lagarde-cruella-2043912

“Multiple juries are in. They’re all reaching the same conclusion,” says Jonathan Haidt, a social psychologist and professor at New York University Stern School of Business. “When social media or high-speed internet came in, [studies] all find the same story, which is mental health plummets, especially for girls.”

https://www.ft.com/content/77d06d3e-2b9f-4d46-814f-da2646fea60c

'Two million Americans don’t have running water. The federal poverty rate — 11.6 per cent in 2021 — has been roughly flat since 1970. Official statistics actually understate the problem because they exclude the more than 1mn in jail.'

https://www.ft.com/content/6218aa73-ae25-46fc-9503-f2f45b8db47f

Op ed by Barney Graham

"We have entered a new era of ‌‌vaccine science, but can we ‌apply our extraordinary technical capabilities toward the goal of improving public health?"

#publichealth #vaccines

https://www.nytimes.com/2023/03/26/opinion/barney-graham-vaccine-science.html

The hummingbird as the Thermus aquaticus of RNA editing tools?

"We exogenously expressed different heterologous ADARs to reveal their distinct editing potential and identified two exceptionally active A-to-I editors: the hummingbird ADAR2, and primarily the mallard-duck ADAR1, whose core body temperature is 40–42°C."

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010661

'Violence is not necessarily an explosion of rage detonated by an individual with a stick, a gun or an army. The most pervasive forms of violence are often no single person’s fault, which is why racism and gender inequality can so often be dismissed as just part of the cultural backdrop. Architecture, the layout of a city, finance, access to food and water, contamination, immobility or forced mobility, limits to educational attainment and other pathologies of power too often appear as the way things are.'
- Paul Farmer
(HT @gregggonsalves)

https://www.noemamag.com/social-medicine-for-a-better-future/

"Olfactory sensory neurons (OSNs) are constantly exposed to pathogens, including viruses. However, serious infection of the brain by the olfactory route rarely occurs. When OSNs detect a virus, they coordinate local antiviral immune responses to stop virus progression into the brain."
#Preprint #Immunology #Neuroimmunology

https://www.biorxiv.org/content/10.1101/2023.03.17.533129v1

Fauci on AIDS before ART

"You’d try to treat the opportunistic infections, but it was like putting a bandaid on a hemorrhage because it was whack-a-mole. Their immune system was destroyed by this unknown virus. You would treat them for one opportunistic infection, and then another one would pop up, and then another one, until finally one would kill them."

https://www.nejm.org/doi/full/10.1056/NEJMp2300938?query=featured_home

'Also, the pressure placed on researchers of LMICs by high-income-country funders to share their data as quickly as possible frequently relegates them to the role of data collectors for better-resourced teams. With enough time, all sorts of locally relevant questions that were not part of the original project could be investigated by local researchers.'

https://www.nature.com/articles/d41586-023-00855-y