Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Nancy Wexler and Huntington’s

If you don’t know her story, I so highly recommend this 5 minute watch. Haunting. Impactful. Motivating.

https://www.pbs.org/kenburns/the-gene/nancy-wexler-haunted-by-a-gene

#neuroscience

Lápiz genético logra la remisión de una leucemia letal en dos adolescentes desahuciados

https://elpais.com/ciencia/2023-06-14/un-lapiz-genetico-logra-la-remision-de-una-leucemia-letal-en-dos-adolescentes-desahuciados.html

Los editores de bases descubiertos en 2016 ya median curaciones

Este es su periplo de descubrimiento a uso en pacientes
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002071
⁦‪@PLOSBiology‬⁩

#ECRs often lack the opportunities to gain #PeerReview skills.
We are here to help!
Take advantage of an opportunity to learn about #OpenPeerReview and help other researchers by giving them helpful feedback on their manuscripts!
Join Crowd Preprint Review groups! 👇

If you are interested in molecular and cellular neurobiology, cancer biology, computational neuroscience, metabolism, or meta-research, check out the link for the details on getting involved!
https://docs.google.com/forms/d/e/1FAIpQLScOR3oM_9OOhRKxjQvupN8YLtaGImOfKskkllrveTWIqrJUVg/viewform

Lobbyists with links to Big Tobacco fund pro-vaping Facebook campaigns https://www.theguardian.com/society/2023/jun/18/lobbyists-with-links-to-big-tobacco-fund-pro-vaping-facebook-campaigns Secretive lobby groups are spreading pro-e-cigarette messages purporting to be grassroots campaigns #vaping #tobacco #interference #socialmedia

"SARS-CoV-2, influenza, RSV, and other respiratory viruses can cause mild and asymptomatic infections, so staff or visitors might not realize they are infected, yet asymptomatic and presymptomatic people can still be contagious and spread infections to patients. Furthermore, despite repeated requests by health care system leaders for symptomatic staff to stay home, “presenteeism” (coming to work despite feeling sick) remains common. Even during the height of the pandemic, some health care systems reported that 50% of staff diagnosed with SARS-CoV-2 worked while symptomatic. Studies from both before and during the pandemic suggest that masking among health care workers can reduce nosocomial respiratory viral infections by approximately 60%"

https://www.nejm.org/doi/full/10.1056/NEJMp2306223?query=TOC&cid=NEJM%20eToc,%20June%2015,%202023%20DM2236702_NEJM_Non_Subscriber&bid=1616356092

"In this article, we show that HIV-infected human microglia express increased levels of TREM1 and are resistant to HIV-induced apoptosis. Moreover, upon genetic inhibition of TREM1, HIV-infected microglia undergo cell death in the absence of increased viral or proinflammatory cytokine expression or the targeting of uninfected cells."

#Infection #Immunity #Virology #HIV #Microglia

https://journals.aai.org/jimmunol/article/doi/10.4049/jimmunol.2300152/265707/HIV-1-Tat-Upregulates-TREM1-Expression-in-Human

Postdoctoral Researcher

Icahn School of Medicine at Mount Sinai

Come join our team as a #bioinformatics postdoc: #multiOmics modeling of #myeloma, including #singleCell, #spatialTranscriptomics and #flowCytometry

See the full job description on jobRxiv: https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-researcher-4/?feed_id=47893

#ScienceJobs #hi...
https://jobrxiv.org/job/icahn-school-of-medicine-at-mount-sinai-27778-postdoctoral-researcher-4/?feed_id=47893

Motivation

"The great literary chronicler of the American South and West was born Charles McCarthy in Providence, Rhode Island, in 1933. He adopted the family nickname Cormac for his writing to avoid confusion with a notorious ventriloquist’s dummy called Charlie McCarthy.

https://www.ft.com/content/9120c16b-5aaf-4ce7-ad6e-843bba55da83"

"The rise in the number of outbreaks of vaccine-derived polio has various causes. The COVID-19 pandemic hindered vaccination campaigns and surveillance. Disasters and conflicts, which often occur in countries vulnerable to polio, have done the same. Moreover, some countries decided to delay their outbreak responses and wait for supplies of the nOPV2 vaccine, rather than use the older type 2 vaccine. A modelling study, originally published in 2021, suggested that this delay would increase the risk of outbreaks occurring"

https://www.nature.com/articles/d41586-023-01953-7

The wordle of science is a lot more depressing than regular wordle⁠ #cartoon #cartoons #comic #comics #instacomic #instacartoon ⁠ #academia #science #research ⁠ #errantscience

As a cell changes size during the cell cycle, why does its density remain constant? https://elifesciences.org/articles/89415?utm_source=twitter&utm_medium=social&utm_campaign=organic_insights

a salad-related tale