Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Immunologists and a control at RU.

Super work on #enhancer - #promoter contacts; nice role for #eRNA in maintaining contacts to promoter bursting too! https://www.nature.com/articles/s41588-023-01442-7

[Fermat's Library] Computers & Automata
https://fermatslibrary.com/s/computers-and-automata

Claude Shannon's 1953 paper addresses then-nascent topics in computation that are profoundly relevant today.

He explores intriguing concepts: whether a machine can learn f. its errors or simulate the human brain.

This paper ignited the imaginations of future A.I. pioneers Marvin Minsky & John McCarthy, signifying its impact on the evolution of computer science.

#ClaudeShannon #ComputerScience #computation #computers #history

Fans of #Celegans will appreciate today's Research Highlight from Journal of Cell Science: Asako Sugimoto and colleagues identify unconventional subunits of the C. elegans γTuC microtubule nucleating complex acquired during its evolution, with important roles in embryonic development and germline maintenance. #microtubules #evolutionarybiology

Discovering divergent γTuC subunits in C. elegans
https://journals.biologists.com/jcs/article/136/13/e136_e1303/323431/Discovering-divergent-gTuC-subunits-in-C-elegans

'Grouping rare disease patients for clinical trials based on the underlying molecular etiology, rather than the traditional, symptom-based definition of disease, has the potential to greatly increase the number of patients gaining access to clinical trials.'

https://www.embopress.org/doi/full/10.15252/emmm.202217159

'Many tech platforms have instituted policies against misinformation or hateful speech that have resulted in content such as election denial, anti-vaccine falsehoods and far-right conspiracy theories being removed – all which tend to skew Republican. But research has found that allegations of anti-conservative bias at social media companies have little empirical evidence, with a 2021 New York University study showing that these platforms’ algorithms instead often work to amplify rightwing content.'

https://www.theguardian.com/world/2023/jul/10/republicans-fuel-the-disinformation-wars

'This stage was reached in the early forties, i.e., at the time when Oswald T. Avery and his collaborators began to work on the transformation of pneumococci, and Delbruck and Luria on the phages of E. coli, although Avery's laboratory was much more receptive to the application of chemistry than was the other group. It is really with Avery that there began what I have called, in my title, the chemical education of genetics. It is, perhaps, characteristic of the way in which science operates that the educator was neither a geneticist nor a chemist. The learning process was slow and weary: the card-carrying members of the guild and their assorted acolytes refused as long as possible, and even beyond that point, to take cognizance.'

https://www.queensu.ca/academia/forsdyke/bioinfo1.htm

"Oppenheimer’s son Peter refused a formal interview, so Sherwin brought his family to the Pecos Wilderness near Santa Fe, saddled up a horse and rode to the Oppenheimers’ rustic cabin, wrangling a chance to talk to the scientist’s son as the two men built a fence. “Marty never thought he was a great interviewer,” said Susan Sherwin, who accompanied him on many research trips, and survives him. But he had a knack for connecting with people.

(A 1963 portrait of J. Robert Oppenheimer, the subject of the biography “American Prometheus” and a new film based on the book.Credit...Eddie Adams/Associated Press)"

https://www.nytimes.com/2023/07/10/books/oppenheimer-american-prometheus-sherwin-bird.html?action=click&module=Well&pgtype=Homepage&section=Book%20Review

On this day in 1863: Albert Calmette was born. He was a pioneer of the BCG vaccine against tuberculosis #ThisDayInBiotech

On this day in 2018: Genetic test found to accurately predict which women with breast cancer should receive chemotherapy #ThisDayInBiotech

All onboard a night train! 🚆

Rail is one of the most sustainable means of transport we have, but cross-border trips account for just 7% of the kilometres travelled by train.

This is why we are supporting 10 pilot projects to create new international train connections in the EU.

They will help us improve the quality of service and make them a viable option for more people.

Discover all the upcoming routes here ➡️ https://europa.eu/!v6b776

📷 AdobeStock

#EuropeanUnion #ConnectingEurope

What makes people cough? @KnowableMag takes a look at how and why we cough, and some of the ways that coughing can go wrong.

Read "New views of a cough: From TB and chronic cough to hope for Parkinson’s"
➡️ https://arevie.ws/CoughKnowable

Take a deeper dive: Read "Infectious and Inflammatory Pathways to Cough" in the Annual Review of Physiology
➡️ https://www.annualreviews.org/doi/10.1146/annurev-physiol-031422-092315

A new 5★ review on #LongCovid immunology
https://nature.com/articles/s41577-023-00904-7

If you are looking for academic communities on #Mastodon then this is a great resource

https://nathanlesage.github.io/academics-on-mastodon/

#AcademicChatter #ScienceMastodon

We see it every night, but the darkness of the night sky baffled scientists for centuries.

⭐ As experts from @UnivParisSaclay, @unicomplutense, @UAM_Madrid + @uwanews write, we can accurately determine the number of stars in the sky – but puzzles remain. https://t.co/PyMOAmaHsG

This is a polymetallic nodule, about the size of a potato, formed over ~2 millions years at the seabed. This is what the fuss is about. This environment changes incredibly slowly, and the plumes of sediment thrown up by mining would spread and settle on distant seabed. But these ecosystems only form where the natural sediment from above is utterly minuscule. Most of the creatures found with the nodules are singletons - just one of their species. #ocean #seabed #nodule