Thiago Carvalho @cyrilpedia@social.cleverlibre.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
The Original artwork and about: https://streetartutopia.com/2023/03/10/champagne-rat-banksys-celebration-of-rebellion-and-marginalized-voices-paris-2018
Street Art by Banksy – A massive Collection (100+ photos): https://streetartutopia.com/2023/01/15/street-art-by-banksy-100-photos-collection/
Thiago Carvalho
boosted
RT @PLOS
Nominations are now open for the @Einstein_Berlin Award for Promoting Quality in Research! Explore past finalists in our newest blog series, now featuring the Ape Research Index from @elisa_bandini and @ForssSofia with @UZH_en 🔎 https://plos.io/3ZVvo5D
Thiago Carvalho
boosted
Referenced link: https://phys.org/news/2023-03-elements.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-03-elements.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1639963490629591044#m
What do the elements sound like? https://phys.org/news/2023-03-elements.html
Fauci on AIDS before ART
"You’d try to treat the opportunistic infections, but it was like putting a bandaid on a hemorrhage because it was whack-a-mole. Their immune system was destroyed by this unknown virus. You would treat them for one opportunistic infection, and then another one would pop up, and then another one, until finally one would kill them."
https://www.nejm.org/doi/full/10.1056/NEJMp2300938?query=featured_home
'Also, the pressure placed on researchers of LMICs by high-income-country funders to share their data as quickly as possible frequently relegates them to the role of data collectors for better-resourced teams. With enough time, all sorts of locally relevant questions that were not part of the original project could be investigated by local researchers.'
Pre ChatGPT, Kurt Vonnegut:
"Stories have very simple shapes, ones that computers can understand."
Thiago Carvalho
boosted
Libraries when you're homeless.
People talking about libraries, and I'd like to add from long-term experience that if you're homeless, those places are vital. Reading the newspaper while sitting on, y'know, a *chair*, hopefully a drinking fountain (No dehydration? Fancy) reading some books, not being too cold or too hot, lovely.
Oh, and you can sort out official stuff, which is handy when you ain't got an address. There was even a lady at one who liked to share food around. Like, you didn't eat it inside, obviously, but food? Nice.
Hell, just about the only things they didn't have were a place to wash or sleep, but you could learn stuff, rest a little, get out of the weather, not be on your guard all the time, (and can't get arrested, cause you're not 'loitering' in a library) and, here's the good part:
You could send your mind somewhere else. Like, without chemicals. You pick up a book and you just escape. That's priceless if you're homeless.
Which is the perfect price, cause you ain't got money.
A heart. A soul. A mind. That's what a library is. And bless em for existing.
Gonna stop there, cause I'm getting all teary and shit.
Thiago Carvalho
boosted
On March 24, 1912, American biochemist Sidney W. Fox was born. In search for the origins of life, Fox explored the synthesis of amino acids from inorganic molecules, the synthesis of proteinous amino acids and amino acid polymers called “proteinoids” from inorganic molecules and thermal energy, and created what he thought was the world‘s first protocell out of proteinoids and water.
http://scihi.org/sidney-fox-origins-life/
#biology #chemistry #biochemistry #proteinoids #historyofscience
"Here we show that heme strongly alters macrophage functional response to AC damage by exacerbating immune cell recruitment and impairing cell efferocytic capacity. In SCD, heme-driven excessive leukocyte influx and defective efferocytosis contribute to exacerbated tissue damage and sustained inflammation."
Thiago Carvalho
boosted
I never thought I would be a #mitochondria nerd, but here we are 🤷♂️🤣. Gonna enjoy reading doing of these articles.
---
RT @CellPressNews
'The new @Molecular_Cell special issue focuses on the #mitochondria. The review articles in this issue focus on the diverse cellular processes involving mitochondria and the approaches used to study them. Take a look. https://hubs.li/Q01J2qN20
https://twitter.com/CellPressNews/status/1639328223816450048
"The paper by White, Wu, and coauthors (10) starts out noting the confusion NSV causes in patient care when persistent viremia appears in someone on ART, then goes on to characterize the virus in four people in care with NSV. Remarkably, the viral populations in all four people contained mutations in the 5′-leader, also known as the 5′ UTR. These mutations inactivated the major splice donor (MSD) site, while still allowing the production of noninfectious virus particles from clonally expanded T cells."
Thiago Carvalho
boosted
Dear Berlin people: don’t forget to vote today. There’s a referendum for making Berlin climate neutral in 2030 (rather than 2045)! Thanks 💚💚💚
Alternative medicine:
"When it came to the treatment of diseases, the ancient Romans had no shortage of magical remedies, several of which involved iron nails. To cure epilepsy, the first-century historian Pliny the Elder advised driving a nail into the ground at the spot where the afflicted person’s head lay at the start of the seizure. The Romans hammered nails into doors to avert plagues and pounded coffin nails into thresholds to keep nightmares at bay. Nails from tombs and crucifixions were sometimes even worn around the neck as talismans against fevers, malaria and evil spells."
https://www.nytimes.com/2023/03/25/science/archaeology-ancient-rome-tomb.html
"In 1965, six years after the invention of the transistor, Moore forecast in a magazine article that the number of transistors and other components on a chip would double every year for the next decade. The prediction, dubbed Moore’s Law by an Intel colleague, has come to exemplify the onrush of technological advance ever since."
https://www.ft.com/content/fd02fefd-5312-432a-b1df-9668b438443d
“There is substantial risk, even if you’ve gotten all the vaccines,” Bernard Black, a law professor at Northwestern University who studies health policy, told me. More than 300 people still die from COVID each day, and the overwhelming majority of them are older. People ages 65 and up are currently hospitalized at nearly 11 times the rate of adults under 50.'
https://www.theatlantic.com/health/archive/2023/03/older-adults-covid-health-quality-of-life/673507/
Tools (#preprint)
"Our platform is built around a commercial instrument and integrates the handling and transfer of samples to and from the instrument, autonomous control of the instrument's software, and the algorithmic generation of sorting gates, resulting in walkaway functionality."
"Tumor-associated neutrophil (TAN) effects on glioblastoma biology remain under-characterized. We show here that 'hybrid' neutrophils with dendritic features - including morphological complexity, expression of antigen presentation genes, and the ability to process exogenous peptide and stimulate MHCII-dependent T cell activation - accumulate intratumorally and suppress tumor growth in vivo."
The Onion absolutely nailing it (again)
@xtaldave They should make the most of these last small distinctions between heir headlines and reality...
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
