Thiago Carvalho @cyrilpedia@social.cleverlibre.org

.@xanderjones82 &co describe Highlighter, an #optogenetic tool for fine-scale eukaryotic #GeneExpression control, and deploy it in #plants to enable cell-level hypothesis testing. @slcuplants @RobertoHofmann1 #PLOSBiology https://plos.io/3RvZvzh

#LongCovid: the doctors’ lives destroyed by an illness they caught while doing their jobs

https://www.bmj.com/content/382/bmj.p1983

Canonical #glycolysis converts glucose into 2x #acetylCoA via eleven biochemical reactions. This study repurposes #phosphoketolase to construct an artificial three-reaction pathway with a theoretical 100% yield of acetyl-CoA from any sugar. #SynBio #PLOSBiology https://plos.io/48sKTH0

A good news story and also a clever real world use of #immunology performing combined #kidney and #bonemarrow #transplant = no need for immunosuppression.

https://news.sky.com/story/girl-8-becomes-first-uk-transplant-patient-not-to-need-life-long-drugs-12966787

A New Pathway to Halt #SARSCoV2 Replication
https://www.hhmi.org/news/human-protein-found-non-immune-cells-defends-against-covid-19?utm_source=twitter&utm_medium=social&utm_content=100004629613513&utm_campaign=news-release
PLSCR1 is a cell-autonomous defence factor against #SARSCoV2 infection
https://www.nature.com/articles/s41586-023-06322-y
Inborn errors of type I IFN immunity in patients with life-threatening #COVID19
https://www.science.org/doi/10.1126/science.abd4570

In which Rish Sunak is shown to ignore long term projections of better financial projections by experts and band things that didn’t exist. Factchecking Rishi Sunak’s claims on the net zero transition https://www.theguardian.com/environment/2023/sep/21/factchecking-rishi-sunak-claims-on-the-net-zero-transition?CMP=Share_iOSApp_Other

This blog summarises our new paper in Public Adminstration, where we take a governance perspective to examine how the recent wave of European climate assemblies have attempted to connect to the complex constellation of actors that make up the climate governance system.

#citizensassemblies #ClimateAssemblies
@democraticinnovations

https://blogs.lse.ac.uk/europpblog/2022/12/07/can-citizen-deliberation-address-the-climate-crisis-not-if-it-is-disconnected-from-politics-and-policymaking/#comments

Let this sink in for a minute...

Of all the mammals on Earth, 96% are livestock and humans.

Only 4% are wild mammals.

Of all birds in the world, 70% are chickens and other poultry, just 30% are wild.

#Nature #Biodiversity #Environment

“Unacceptable funding inequities have forced many of our nation’s distinguished Historically Black Colleges and Universities to operate with inadequate resources and delay critical investments in everything from campus infrastructure to research and development to student support services”

https://www.theatlantic.com/ideas/archive/2023/09/land-grant-colleges-underfunded-biden-administration/675379/

'Ms. Yusuf is one in a legion of more than three million community health workers globally and is one of a small minority that are actually paid anything at all. Eighty-six percent of community health workers in Africa are completely unpaid.'

https://www.nytimes.com/2023/09/21/health/community-health-worker-pay.html

'Though humans have lived alongside mice for at least 15,000 years, few of us have ever heard mice sing, because they do so in frequencies beyond the range detectable by human hearing.'

https://www.nytimes.com/2023/09/20/magazine/animal-communication.html

"These studies demonstrate how a protein domain that enhances colonization of microorganisms in the marine environment can also enhance colonization in humans and identify a peptide that can inhibit V. cholerae virulence."

https://www.pnas.org/doi/10.1073/pnas.2308238120

Sheffield is hiring! 4 x Research Fellow #newPI positions available in biophysics and quantitative biology (incl mechanobiology)

I can say from experience that Sheffield is a great place to start a research group

Pls share!

https://www.sheffield.ac.uk/science/news/latest-vacancies-faculty-science

Nikki Haley and Tim Scott are here to remind you Republicans hate unions https://www.motherjones.com/politics/2023/09/nikki-haley-tim-scott-uaw-strike-autoworkers-donald-trump-detroit/

“So each time you are infected with Covid, you are rolling the dice on long Covid, whether it’s a first infection or second or third or so on?”

“That’s correct”

-Ziyad Al-Aly, chief of research at the VA St. Louis Healthcare System and clinical epidemiologist at Washington University in St. Louis. - (paywall bypass link) - https://archive.md/2023.09.21-071143/https://www.statnews.com/2023/09/20/do-long-covid-odds-increase-with-second-infection/