Thiago Carvalho @cyrilpedia@social.cleverlibre.org

Karma chamaleon.
Prato falante.
Glazed #stoneware by @hunchbacksociety

#proverbs #proverbios #ceramics #plate #pottery #artgallery #artstagram

https://madalenaparreira.com/Hunchbacksociety

"Congress has an opportunity to turn this ongoing human tragedy into a public health advancement, by providing support for a five-year project to eliminate hepatitis C in the United States. But the time available for approval is growing short."

https://www.nytimes.com/2023/11/28/opinion/hepatitis-c-eliminate.html

"The non-profit I described was the governing structure that OpenAI began with in 2015, when it was formed as a research-oriented non-profit to build safe AI technology.

But ever since OpenAI’s ChatGPT looked to be on its way to achieving the holy grail of tech – an at-scale consumer platform that would generate billions of dollars in profits – its non-profit safety mission has been endangered by big money."

https://www.theguardian.com/commentisfree/2023/nov/28/artificial-intelligence-openai-non-profit-money

"Here we show that deletion of ST2, the receptor for interleukin (IL)-33, on Treg cells increased granulocyte influx into the lung and increased cytokine production by innate lymphoid and γδ T cells without alteration of adaptive immunity to influenza."
#immunology #MucosalImmunology

https://www.nature.com/articles/s41590-023-01655-2

"Although these systems hold great promise for advancing our understanding of lung biology and disease, there are still many challenges, including efficient derivation of terminal cellular maturity and structural complexity, as well as developing standardized workflows for scalability and reproducibility. Here, we outline the most recent developments in lung organoid systems and their implications for disease modeling that could set the stage for further breakthroughs in this exciting and rapidly evolving field."
#Organoids

https://www.jci.org/articles/view/170500

"I'm not particularly impressed with Large Language Models as they apply to natural human languages - "plausible sentence generators" is the phrase that I've seen that sums up my beliefs about them. But for things that are less complex than natural language, these techniques have more real-world uses. Coding is one, naturally, because programming languages are smaller and more orderly than human ones. The language of protein sequences is another example"

https://www.science.org/content/blog-post/ai-hypotheses

'He told me he had started writing the song for a prospective musical version of Nosferatu years before, but never finished it. Around the time we were recording, Meat Loaf had lost his voice, and after it was a hit he always used to say: “Dang. That song should have been mine!”

https://www.theguardian.com/culture/2023/nov/27/bonnie-tyler-total-eclipse-of-the-heart-nosferatu-musical

"The sparse and stochastic nature of reprogramming has obscured our understanding of how transcription factors drive cells to new identities. To overcome this limit, we developed a compact, portable reprogramming system that increases direct conversion of fibroblasts to motor neurons by two orders of magnitude"

#preprint

https://www.biorxiv.org/content/10.1101/2023.11.26.568736v1